the BsaI paper is a good starter for the enzyme rabbit hole, but it was a dead end. Those 2 sites are found at the exact same location in similar Chinese bat CoV (RpYN06)
Look up George Webb’s reporting on tv r original leak from fort Detrick likely by the hands of Sina Bavari perhaps exchanged with shi Zhengli at a South African wef event
I follow him but try to avoid crazy rabbit holes. This was an R&D accident and easy to coverup b/c fewer than a dozen virologists worked on it (Baric at UNC, Dani in BSL4, Linfa in Singapore, Munster in Montana, etc). Basically Fauci funded DARPA Defuse via his $82M CREID project awarded in 2019.
So why did the Chinese participate in the cover-up?
Another more likely possibility: SARS-CoV-2 was created to test the protective activity of the SARS vaccine in transgenic animals. WIV workers had only to insert a new fragment made by Baric (FCS). HIV "inserts" were acquired by selective pressure during experiments with spike HIV pseudotypes for optimisation of interaction with hACE2.
Try to answer this tough question in post #4. A preview:
So what caused the US Government to hop in bed with the Chinese government and cover up a lab leak? Break the question into two pieces for clarity. So yes China covered up the lab leak but Fauci, and his US Government army of virologists, covered up what leaked.
I've read somewhere that an unofficial sequence of SARS-CoV-2 was shared by a small group of Western scientists on Jan 5. This doesn't make a great difference on this matter if this was this date.
How do you know that Danielle Anderson was patient 0?
This doesn't mean that Danielle Anderson was patient 0. This opens the possibility that SARS-CoV-2 or another related virus has been brought to WIV by Danielle Anderson. The virus could have been modified (or not, if it was already SARS-CoV-2) in WIV, tested in Rhinolophus, and, after failure of infection, in another species which contaminated the lab worker.
that paper only shows infection (via injection) but no transmission. It talks about fecal-oral but Covid is airborne. 0 papers showing transmission in lab mice (hACE2, humanized, etc).
"Although appropriate mouse models for studying SC2 transmission have not been reported" as of late 2021
lab “mice don’t sneeze”, so they don’t transmit these diseases through the air. And process of adapting these viruses to mice actually makes the germs less able to infect human cells. They’re safer”
The fact that SARS-CoV-2 cannot infect hACE2 mice do not prove that the aim of SARS-CoV-2 was not to test the vaccine. They could not know it would not infect them before using it. Maybe they have tried to infect another species when they saw they could not infect the mice and that's how the accident occurred.
They concluded: it would be interesting to perform an experimental inoculation study using Chinese horseshoe bats, from which WIV1-CoV was originally isolated, to investigate if more efficient virus replication and shedding can be observed in these animals.
This is the best piece of inquiry I've ever read. I took the liberty to translate it into French for my blog: http://skidmark.blog/2024/06/29/une-sequence-consensuelle-des-evenements-lies-au-sars-par-jim-haslan/ *
... and published it just after my translation of Will Jones article about your work: http://skidmark.blog/2024/06/29/serait-ce-cet-homme-qui-a-cree-le-covid-19-dans-le-laboratoire-americain-de-fauci-par-will-jones/
I assumed you wouldn't mind!
(*) There's a typo in your name only in the link, not in the article itself
Laissez les bons temps rouler!
Love your work Jim! Is this claim by Alex Washburne about Ben Hu correct? And is it relevant?
"Ben Hu (2017) is the only person to have used BsaI + BsmBI enzymes together for engineering SARS-CoVs." https://twitter.com/WashburneAlex/status/1734723144303190257
Thanks for reading Richard!
the BsaI paper is a good starter for the enzyme rabbit hole, but it was a dead end. Those 2 sites are found at the exact same location in similar Chinese bat CoV (RpYN06)
https://twitter.com/search?f=live&q=RpYN06%20(from%3AWashburneAlex)&src=typed_query
BsaI is also designed to removed, so it is actually MORE work to leave them in
https://x.com/Friedemann1/status/1583520013864308736?s=20
The only relevant restriction site in SARS2 is BsaXI
https://zenodo.org/records/7742605
BsaXI flanks the out-of-frame furin cleavage site (PRRAR) and forces the Proline,
https://x.com/Ayjchan/status/1278435011138654209?s=20
These are 2 arguments used by zoonati to claim natural origin!
https://x.com/tony_vandongen/status/1723711090079470011?s=20
It was published by Baric at UNC in 2017 and BsaXI was designed to be "retained"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7120940/
Baric was asked by US military of any restriction sites, but said no
https://usrtk.org/wp-content/uploads/2020/12/Baric_bioengineer_Baric-Files.pdf
Finally, the guy who leaked Ben Hu's name (David Asher) got a Chinese name backwards and was an internet rumor, that he himself may not believe
https://x.com/jhas5/status/1671670420271931393?s=20
anyone care the president of UNC at the time is now prez at USC where NIH $ has skyrocketed?
Look up George Webb’s reporting on tv r original leak from fort Detrick likely by the hands of Sina Bavari perhaps exchanged with shi Zhengli at a South African wef event
I follow him but try to avoid crazy rabbit holes. This was an R&D accident and easy to coverup b/c fewer than a dozen virologists worked on it (Baric at UNC, Dani in BSL4, Linfa in Singapore, Munster in Montana, etc). Basically Fauci funded DARPA Defuse via his $82M CREID project awarded in 2019.
So why did the Chinese participate in the cover-up?
Another more likely possibility: SARS-CoV-2 was created to test the protective activity of the SARS vaccine in transgenic animals. WIV workers had only to insert a new fragment made by Baric (FCS). HIV "inserts" were acquired by selective pressure during experiments with spike HIV pseudotypes for optimisation of interaction with hACE2.
Try to answer this tough question in post #4. A preview:
So what caused the US Government to hop in bed with the Chinese government and cover up a lab leak? Break the question into two pieces for clarity. So yes China covered up the lab leak but Fauci, and his US Government army of virologists, covered up what leaked.
Both covered up what leaked. If the virus had been brought by the US, the Chinese would have done everything to characterize the first cases.
R&D accident, maybe 6 knew of genome before Jan 10, 2020. Danielle Anderson, listed on DARPA Defuse and inside BSL4 most of 2019, was patient 0.
I've read somewhere that an unofficial sequence of SARS-CoV-2 was shared by a small group of Western scientists on Jan 5. This doesn't make a great difference on this matter if this was this date.
How do you know that Danielle Anderson was patient 0?
she lied, claimed to be working on Ebola while in Wuhan but 0 publications
https://www.researchgate.net/profile/Danielle-Anderson-8
Dani and Linfa were cross referencing Baric's 'consensus' work (ie DARPA bid) in 2019
https://www.sciencedirect.com/science/article/pii/S187962571830107X?via%3Dihub
and Dani was part of Fauci's $82M CREID (aka DARPA Defuse) network in 2019:
https://twitter.com/BillyBostickson/status/1313513326987546625?s=20&t=L9RQ5t3zkWeBzNpbIeEUDA
This doesn't mean that Danielle Anderson was patient 0. This opens the possibility that SARS-CoV-2 or another related virus has been brought to WIV by Danielle Anderson. The virus could have been modified (or not, if it was already SARS-CoV-2) in WIV, tested in Rhinolophus, and, after failure of infection, in another species which contaminated the lab worker.
So why did the Chinese participate in the cover-up?
Another more likely possibility: SARS-CoV-2 was created to test the protective activity of the SARS vaccine in transgenic animals.
WIV workers had only to insert a new fragment made by Baric (FCS).
HIV "inserts" were acquired by selective pressure during experiments with spike HIV pseudotypes for optimisation of interaction with hACE2.
Re HIV inserts it's linked above but found in both RaTG13 and Banal-52
https://twitter.com/tony_vandongen/status/1544517096071110656?s=20&t=kEabRrRlh9PPp-kECQrE6A
SARS2 (wild type) does not infect lab mice
https://pubmed.ncbi.nlm.nih.gov/34835069/
SARS2 does not transmit in 'humanized mice'
Where is it shown that SARS2 cannot infect hACE2 mice ?
The presence of HIV "inserts" in BANAL-52 and RaTG13 could mean that they are not wild type virus.
Common laboratory mice would be well-suited for this purpose but are not susceptible to infection with wild-type SARS-CoV-2.
https://pubmed.ncbi.nlm.nih.gov/34835069/
per Baric
https://www.youtube.com/watch?v=BZe-7BRLZtI&t=3710s
https://www.statnews.com/2020/03/05/coronavirus-labs-scramble-to-find-right-animals-for-covid-19-studies/
https://pubmed.ncbi.nlm.nih.gov/32485164/
"both young and aged hACE2 mice sustained high viral loads in lung, trachea, and brain upon intranasal infection. "
Received April 14, 2020
don't conflate infection with transmission
that paper only shows infection (via injection) but no transmission. It talks about fecal-oral but Covid is airborne. 0 papers showing transmission in lab mice (hACE2, humanized, etc).
"Although appropriate mouse models for studying SC2 transmission have not been reported" as of late 2021
https://onlinelibrary.wiley.com/doi/full/10.1002/mco2.98
lab “mice don’t sneeze”, so they don’t transmit these diseases through the air. And process of adapting these viruses to mice actually makes the germs less able to infect human cells. They’re safer”
https://www.npr.org/sections/health-shots/2014/11/07/361219361/how-a-tilt-toward-safety-stopped-a-scientists-virus-research
if a coronavirus lab mouse infects lab tech there is 0 transmission:
https://www.propublica.org/article/here-are-six-accidents-unc-researchers-had-with-lab-created-coronaviruses
The fact that SARS-CoV-2 cannot infect hACE2 mice do not prove that the aim of SARS-CoV-2 was not to test the vaccine. They could not know it would not infect them before using it. Maybe they have tried to infect another species when they saw they could not infect the mice and that's how the accident occurred.
SARS2 transmits in Egyptian fruit bats showing "characteristics of a reservoir host"
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30089-6/fulltext
Baric and Munster were infecting Egyptian fruit bats in 2018 at Fauci's Montana biolab (just after DARPA rejected Defuse)
https://www.mdpi.com/1999-4915/10/12/727
They concluded: it would be interesting to perform an experimental inoculation study using Chinese horseshoe bats, from which WIV1-CoV was originally isolated, to investigate if more efficient virus replication and shedding can be observed in these animals.
So why did the Chinese participate in the cover-up?
Another more likely possibility: SARS-CoV-2 was created to test the protective activity of the SARS vaccine in transgenic animals.
WIV workers had only to insert a new fragment made by Baric (FCS).
HIV "inserts" were acquired by selective pressure during experiments with spike HIV pseudotypes for optimisation of interaction with hACE2.
So why did the Chinese participate in the cover-up?
Another more likely possibility: SARS-CoV-2 was created to test the protective activity of the SARS vaccine in transgenic animals.
WIV workers had only to insert a new fragment made by Baric (FCS).
HIV "inserts" were acquired by selective pressure during experiments with spike HIV pseudotypes for optimisation of interaction with hACE2.
The PBS ONLINE special "China's COVID Secrets" has been removed from most sites but some kind souls uploaded a copy: https://youtu.be/Ar865Xmna2s
I'll be watching it to compare with the version aired by the BBC (and now also restricted to UK iPlayer viewers) "54 Days: China and the Pandemic"
Here's a similar USA PBS version
https://www.youtube.com/watch?v=zzbcG7CRYgQ
with Eddie clips
https://www.youtube.com/watch?v=zzbcG7CRYgQ&t=590s
https://www.youtube.com/watch?v=zzbcG7CRYgQ&t=1939s
None of those links are available for me, might be US/NAm only. That's why I posted an alternative link for the one in your article.
Better put a copy on Rumble to avoid censorship!